![]() Consistent with US Preventive Task Force guidelines, references were evaluated for quality based on the highest level of evidence. ![]() Grading of Recommendations Assessment, Development, and Evaluation (GRADE) methodology was used for defining the strength of recommendations and rating quality of the evidence. ![]() Evidence reports and published guidelines were also reviewed, and additional studies were located by reviewing bibliographies of identified articles. Abstracts of research presented at symposia and scientific conferences were not considered adequate for inclusion. Priority was given to articles reporting original research, in particular randomized controlled trials, although review articles and commentaries were consulted. The search was restricted to English-language articles published from 1966 through March 2015. We sought to provide evidence-based guidelines regarding the diagnosis and management of amniotic fluid embolism.Ī systematic literature review was performed using MEDLINE, PubMed, EMBASE, and the Cochrane Library.
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